
Scilex Holding Company (NASDAQ: SCLX) Stock Competitors & Peer Comparison
See SCLX's competitors and their performance on the NASDAQ and across the wider stock market.
Peer Comparison Table: Drug Manufacturers - General Industry
Detailed financial metrics including price, market cap, P/E ratio, and more for SCLX and its NASDAQ peers.
| Symbol | Price | Change % | Market Cap | P/E Ratio | EPS | Dividend Yield |
|---|---|---|---|---|---|---|
| SCLX | $5.43 | -2.51% | 46.1M | -0.14 | -$38.95 | N/A |
| LLY | $1,172.86 | -0.28% | 1.1T | 37.28 | $31.49 | +0.57% |
| JNJ | $268.04 | -0.73% | 640.5B | 24.77 | $10.73 | +1.98% |
| ABBV | $255.48 | -1.03% | 451.4B | 25.07 | $10.19 | +2.67% |
| MRK | $148.35 | -0.80% | 366.3B | 46.20 | $3.21 | +2.27% |
| NVS | $153.81 | -0.54% | 292.3B | 17.70 | $8.69 | +3.09% |
| AZN | $162.70 | -1.11% | 252.3B | 17.57 | $9.26 | +1.29% |
| AMGN | $432.42 | -1.05% | 233.4B | 19.33 | $22.37 | +2.30% |
| NVO | $45.61 | -1.41% | 202.5B | 11.34 | $4.02 | +2.56% |
| GILD | $145.68 | -2.14% | 180.9B | -373.54 | -$0.39 | +2.22% |
Stock Comparison
Eli Lilly and Company (NYSE: LLY)
SCLX vs LLY Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, LLY has a market cap of 1.1T. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while LLY trades at $1,172.86.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas LLY's P/E ratio is 37.28. In terms of profitability, SCLX's ROE is +1.90%, compared to LLY's ROE of +0.93%. Regarding short-term risk, SCLX is more volatile compared to LLY. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check LLY's competition here
Johnson & Johnson (NYSE: JNJ)
SCLX vs JNJ Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, JNJ has a market cap of 640.5B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while JNJ trades at $268.04.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas JNJ's P/E ratio is 24.77. In terms of profitability, SCLX's ROE is +1.90%, compared to JNJ's ROE of +0.26%. Regarding short-term risk, SCLX is more volatile compared to JNJ. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check JNJ's competition here
AbbVie Inc. (NYSE: ABBV)
SCLX vs ABBV Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, ABBV has a market cap of 451.4B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while ABBV trades at $255.48.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas ABBV's P/E ratio is 25.07. In terms of profitability, SCLX's ROE is +1.90%, compared to ABBV's ROE of -1.36%. Regarding short-term risk, SCLX is more volatile compared to ABBV. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check ABBV's competition here
Merck & Co., Inc. (NYSE: MRK)
SCLX vs MRK Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, MRK has a market cap of 366.3B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while MRK trades at $148.35.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas MRK's P/E ratio is 46.20. In terms of profitability, SCLX's ROE is +1.90%, compared to MRK's ROE of +0.07%. Regarding short-term risk, SCLX is more volatile compared to MRK. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check MRK's competition here
Novartis AG (NYSE: NVS)
SCLX vs NVS Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, NVS has a market cap of 292.3B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while NVS trades at $153.81.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas NVS's P/E ratio is 17.70. In terms of profitability, SCLX's ROE is +1.90%, compared to NVS's ROE of +0.30%. Regarding short-term risk, SCLX is more volatile compared to NVS. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check NVS's competition here
AstraZeneca PLC (NYSE: AZN)
SCLX vs AZN Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, AZN has a market cap of 252.3B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while AZN trades at $162.70.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas AZN's P/E ratio is 17.57. In terms of profitability, SCLX's ROE is +1.90%, compared to AZN's ROE of +0.22%. Regarding short-term risk, SCLX is more volatile compared to AZN. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check AZN's competition here
Amgen Inc. (NASDAQ: AMGN)
SCLX vs AMGN Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, AMGN has a market cap of 233.4B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while AMGN trades at $432.42.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas AMGN's P/E ratio is 19.33. In terms of profitability, SCLX's ROE is +1.90%, compared to AMGN's ROE of +0.89%. Regarding short-term risk, SCLX is more volatile compared to AMGN. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check AMGN's competition here
Novo Nordisk A/S (NYSE: NVO)
SCLX vs NVO Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, NVO has a market cap of 202.5B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while NVO trades at $45.61.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas NVO's P/E ratio is 11.34. In terms of profitability, SCLX's ROE is +1.90%, compared to NVO's ROE of +0.59%. Regarding short-term risk, SCLX is more volatile compared to NVO. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check NVO's competition here
Gilead Sciences, Inc. (NASDAQ: GILD)
SCLX vs GILD Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, GILD has a market cap of 180.9B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while GILD trades at $145.68.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas GILD's P/E ratio is -373.54. In terms of profitability, SCLX's ROE is +1.90%, compared to GILD's ROE of -0.16%. Regarding short-term risk, SCLX is more volatile compared to GILD. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check GILD's competition here
Pfizer Inc. (NYSE: PFE)
SCLX vs PFE Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, PFE has a market cap of 159.4B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while PFE trades at $27.96.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas PFE's P/E ratio is 9.17. In terms of profitability, SCLX's ROE is +1.90%, compared to PFE's ROE of +0.05%. Regarding short-term risk, SCLX is more volatile compared to PFE. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check PFE's competition here
Bristol-Myers Squibb Company (NYSE: BMY)
SCLX vs BMY Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, BMY has a market cap of 136B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while BMY trades at $66.58.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas BMY's P/E ratio is 11.23. In terms of profitability, SCLX's ROE is +1.90%, compared to BMY's ROE of +0.47%. Regarding short-term risk, SCLX is more volatile compared to BMY. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check BMY's competition here
Sanofi (NASDAQ: SNY)
SCLX vs SNY Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, SNY has a market cap of 107.6B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while SNY trades at $44.82.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas SNY's P/E ratio is 9.76. In terms of profitability, SCLX's ROE is +1.90%, compared to SNY's ROE of +0.06%. Regarding short-term risk, SCLX is more volatile compared to SNY. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check SNY's competition here
GSK plc (NYSE: GSK)
SCLX vs GSK Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, GSK has a market cap of 101.8B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while GSK trades at $50.82.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas GSK's P/E ratio is 10.98. In terms of profitability, SCLX's ROE is +1.90%, compared to GSK's ROE of +0.24%. Regarding short-term risk, SCLX is more volatile compared to GSK. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check GSK's competition here
Biogen Inc. (NASDAQ: BIIB)
SCLX vs BIIB Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, BIIB has a market cap of 32.3B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while BIIB trades at $218.50.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas BIIB's P/E ratio is 13.79. In terms of profitability, SCLX's ROE is +1.90%, compared to BIIB's ROE of +0.05%. Regarding short-term risk, SCLX is more volatile compared to BIIB. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check BIIB's competition here
Horizon Therapeutics Public Limited Company (NASDAQ: HZNP)
SCLX vs HZNP Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, HZNP has a market cap of 26.6B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while HZNP trades at $116.30.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas HZNP's P/E ratio is 61.86. In terms of profitability, SCLX's ROE is +1.90%, compared to HZNP's ROE of +0.11%. Regarding short-term risk, SCLX is more volatile compared to HZNP. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check HZNP's competition here
Grifols, S.A. (NASDAQ: GRFS)
SCLX vs GRFS Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, GRFS has a market cap of 6.5B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while GRFS trades at $7.69.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas GRFS's P/E ratio is 8.83. In terms of profitability, SCLX's ROE is +1.90%, compared to GRFS's ROE of +0.08%. Regarding short-term risk, SCLX is more volatile compared to GRFS. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check GRFS's competition here
Organon & Co. (NYSE: OGN)
SCLX vs OGN Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, OGN has a market cap of 3.6B. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while OGN trades at $13.76.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas OGN's P/E ratio is 4.11. In terms of profitability, SCLX's ROE is +1.90%, compared to OGN's ROE of +0.23%. Regarding short-term risk, SCLX is more volatile compared to OGN. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check OGN's competition here
Amarin Corporation plc (NASDAQ: AMRN)
SCLX vs AMRN Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, AMRN has a market cap of 288.9M. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while AMRN trades at $13.97.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas AMRN's P/E ratio is -139.70. In terms of profitability, SCLX's ROE is +1.90%, compared to AMRN's ROE of -0.06%. Regarding short-term risk, SCLX is more volatile compared to AMRN. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check AMRN's competition here
Scilex Holding Company (NASDAQ: SCLXW)
SCLX vs SCLXW Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, SCLXW has a market cap of 42.1M. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while SCLXW trades at $0.16.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas SCLXW's P/E ratio is N/A. In terms of profitability, SCLX's ROE is +1.90%, compared to SCLXW's ROE of +1.90%. Regarding short-term risk, SCLX is more volatile compared to SCLXW. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check SCLXW's competition here
MIRA Pharmaceuticals, Inc. (NASDAQ: MIRA)
SCLX vs MIRA Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, MIRA has a market cap of 31.5M. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while MIRA trades at $0.75.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas MIRA's P/E ratio is -0.52. In terms of profitability, SCLX's ROE is +1.90%, compared to MIRA's ROE of -1.07%. Regarding short-term risk, SCLX is more volatile compared to MIRA. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check MIRA's competition here
BioDelivery Sciences Intl, Inc. Wrrt (NASDAQ: BDSIW)
SCLX vs BDSIW Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, BDSIW has a market cap of 0. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while BDSIW trades at $0.04.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas BDSIW's P/E ratio is -0.43. In terms of profitability, SCLX's ROE is +1.90%, compared to BDSIW's ROE of +0.57%. Regarding short-term risk, SCLX is less volatile compared to BDSIW. This indicates lower risk in terms of short-term price fluctuations for SCLX.Check BDSIW's competition here
Clarus Therapeutics Holdings, Inc. (NASDAQ: CRXT)
SCLX vs CRXT Comparison August 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 46.1M. In comparison, CRXT has a market cap of 0. Regarding current trading prices, SCLX is priced at $5.43 on the NASDAQ, while CRXT trades at $0.05.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.14, whereas CRXT's P/E ratio is -0.02. In terms of profitability, SCLX's ROE is +1.90%, compared to CRXT's ROE of -4.63%. Regarding short-term risk, SCLX is less volatile compared to CRXT. This indicates lower risk in terms of short-term price fluctuations for SCLX.Check CRXT's competition here