Scilex Holding Company (NASDAQ: SCLX) Stock Competitors & Peer Comparison
See SCLX's competitors and their performance on the NASDAQ and across the wider stock market.
Peer Comparison Table: Drug Manufacturers - General Industry
Detailed financial metrics including price, market cap, P/E ratio, and more for SCLX and its NASDAQ peers.
| Symbol | Price | Change % | Market Cap | P/E Ratio | EPS | Dividend Yield |
|---|---|---|---|---|---|---|
| SCLX | $5.04 | -6.15% | 42.8M | -0.13 | -$38.95 | N/A |
| LLY | $1,152.22 | -0.02% | 1.1T | 36.61 | $31.49 | +0.58% |
| JNJ | $269.99 | -0.09% | 650.6B | 25.16 | $10.73 | +1.94% |
| ABBV | $263.78 | -0.09% | 466.1B | 25.89 | $10.19 | +2.58% |
| MRK | $146.76 | -0.27% | 362.5B | 45.72 | $3.21 | +2.32% |
| NVS | $140.37 | -0.39% | 266.8B | 16.15 | $8.69 | +3.38% |
| AZN | $166.08 | -0.04% | 257.5B | 17.93 | $9.26 | +1.94% |
| AMGN | $385.65 | +2.47% | 205B | 16.98 | $22.37 | +2.58% |
| NVO | $43.24 | +0.12% | 192B | 10.76 | $4.02 | +4.13% |
| GILD | $150.11 | -0.52% | 186.4B | -384.90 | -$0.39 | +2.15% |
Stock Comparison
Eli Lilly and Company (NYSE: LLY)
SCLX vs LLY Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, LLY has a market cap of 1.1T. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while LLY trades at $1,152.22.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas LLY's P/E ratio is 36.61. In terms of profitability, SCLX's ROE is +1.90%, compared to LLY's ROE of +0.93%. Regarding short-term risk, SCLX is more volatile compared to LLY. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check LLY's competition here
Johnson & Johnson (NYSE: JNJ)
SCLX vs JNJ Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, JNJ has a market cap of 650.6B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while JNJ trades at $269.99.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas JNJ's P/E ratio is 25.16. In terms of profitability, SCLX's ROE is +1.90%, compared to JNJ's ROE of +0.26%. Regarding short-term risk, SCLX is more volatile compared to JNJ. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check JNJ's competition here
AbbVie Inc. (NYSE: ABBV)
SCLX vs ABBV Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, ABBV has a market cap of 466.1B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while ABBV trades at $263.78.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas ABBV's P/E ratio is 25.89. In terms of profitability, SCLX's ROE is +1.90%, compared to ABBV's ROE of -1.36%. Regarding short-term risk, SCLX is more volatile compared to ABBV. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check ABBV's competition here
Merck & Co., Inc. (NYSE: MRK)
SCLX vs MRK Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, MRK has a market cap of 362.5B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while MRK trades at $146.76.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas MRK's P/E ratio is 45.72. In terms of profitability, SCLX's ROE is +1.90%, compared to MRK's ROE of +0.07%. Regarding short-term risk, SCLX is more volatile compared to MRK. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check MRK's competition here
Novartis AG (NYSE: NVS)
SCLX vs NVS Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, NVS has a market cap of 266.8B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while NVS trades at $140.37.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas NVS's P/E ratio is 16.15. In terms of profitability, SCLX's ROE is +1.90%, compared to NVS's ROE of +0.30%. Regarding short-term risk, SCLX is more volatile compared to NVS. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check NVS's competition here
AstraZeneca PLC (NYSE: AZN)
SCLX vs AZN Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, AZN has a market cap of 257.5B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while AZN trades at $166.08.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas AZN's P/E ratio is 17.93. In terms of profitability, SCLX's ROE is +1.90%, compared to AZN's ROE of +0.22%. Regarding short-term risk, SCLX is more volatile compared to AZN. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check AZN's competition here
Amgen Inc. (NASDAQ: AMGN)
SCLX vs AMGN Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, AMGN has a market cap of 205B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while AMGN trades at $385.65.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas AMGN's P/E ratio is 16.98. In terms of profitability, SCLX's ROE is +1.90%, compared to AMGN's ROE of +0.89%. Regarding short-term risk, SCLX is more volatile compared to AMGN. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check AMGN's competition here
Novo Nordisk A/S (NYSE: NVO)
SCLX vs NVO Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, NVO has a market cap of 192B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while NVO trades at $43.24.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas NVO's P/E ratio is 10.76. In terms of profitability, SCLX's ROE is +1.90%, compared to NVO's ROE of +0.59%. Regarding short-term risk, SCLX is more volatile compared to NVO. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check NVO's competition here
Gilead Sciences, Inc. (NASDAQ: GILD)
SCLX vs GILD Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, GILD has a market cap of 186.4B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while GILD trades at $150.11.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas GILD's P/E ratio is -384.90. In terms of profitability, SCLX's ROE is +1.90%, compared to GILD's ROE of -0.16%. Regarding short-term risk, SCLX is more volatile compared to GILD. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check GILD's competition here
Pfizer Inc. (NYSE: PFE)
SCLX vs PFE Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, PFE has a market cap of 157.3B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while PFE trades at $27.66.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas PFE's P/E ratio is 9.05. In terms of profitability, SCLX's ROE is +1.90%, compared to PFE's ROE of +0.05%. Regarding short-term risk, SCLX is more volatile compared to PFE. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check PFE's competition here
Bristol-Myers Squibb Company (NYSE: BMY)
SCLX vs BMY Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, BMY has a market cap of 128.8B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while BMY trades at $63.06.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas BMY's P/E ratio is 10.63. In terms of profitability, SCLX's ROE is +1.90%, compared to BMY's ROE of +0.47%. Regarding short-term risk, SCLX is more volatile compared to BMY. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check BMY's competition here
Sanofi (NASDAQ: SNY)
SCLX vs SNY Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, SNY has a market cap of 102B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while SNY trades at $42.48.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas SNY's P/E ratio is 9.25. In terms of profitability, SCLX's ROE is +1.90%, compared to SNY's ROE of +0.06%. Regarding short-term risk, SCLX is more volatile compared to SNY. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check SNY's competition here
GSK plc (NYSE: GSK)
SCLX vs GSK Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, GSK has a market cap of 100.6B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while GSK trades at $50.22.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas GSK's P/E ratio is 10.85. In terms of profitability, SCLX's ROE is +1.90%, compared to GSK's ROE of +0.24%. Regarding short-term risk, SCLX is more volatile compared to GSK. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check GSK's competition here
Biogen Inc. (NASDAQ: BIIB)
SCLX vs BIIB Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, BIIB has a market cap of 31.8B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while BIIB trades at $215.50.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas BIIB's P/E ratio is 13.60. In terms of profitability, SCLX's ROE is +1.90%, compared to BIIB's ROE of +0.05%. Regarding short-term risk, SCLX is more volatile compared to BIIB. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check BIIB's competition here
Horizon Therapeutics Public Limited Company (NASDAQ: HZNP)
SCLX vs HZNP Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, HZNP has a market cap of 26.6B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while HZNP trades at $116.30.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas HZNP's P/E ratio is 61.86. In terms of profitability, SCLX's ROE is +1.90%, compared to HZNP's ROE of +0.11%. Regarding short-term risk, SCLX is more volatile compared to HZNP. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check HZNP's competition here
Grifols, S.A. (NASDAQ: GRFS)
SCLX vs GRFS Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, GRFS has a market cap of 6.2B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while GRFS trades at $7.31.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas GRFS's P/E ratio is 8.40. In terms of profitability, SCLX's ROE is +1.90%, compared to GRFS's ROE of +0.08%. Regarding short-term risk, SCLX is more volatile compared to GRFS. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check GRFS's competition here
Organon & Co. (NYSE: OGN)
SCLX vs OGN Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, OGN has a market cap of 3.6B. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while OGN trades at $13.68.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas OGN's P/E ratio is 4.09. In terms of profitability, SCLX's ROE is +1.90%, compared to OGN's ROE of +0.23%. Regarding short-term risk, SCLX is more volatile compared to OGN. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check OGN's competition here
Amarin Corporation plc (NASDAQ: AMRN)
SCLX vs AMRN Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, AMRN has a market cap of 286.9M. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while AMRN trades at $13.63.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas AMRN's P/E ratio is -138.70. In terms of profitability, SCLX's ROE is +1.90%, compared to AMRN's ROE of -0.06%. Regarding short-term risk, SCLX is more volatile compared to AMRN. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check AMRN's competition here
MIRA Pharmaceuticals, Inc. (NASDAQ: MIRA)
SCLX vs MIRA Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, MIRA has a market cap of 34.2M. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while MIRA trades at $0.83.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas MIRA's P/E ratio is -0.56. In terms of profitability, SCLX's ROE is +1.90%, compared to MIRA's ROE of -1.07%. Regarding short-term risk, SCLX is more volatile compared to MIRA. This indicates higher risk in terms of short-term price fluctuations for SCLX.Check MIRA's competition here
Scilex Holding Company (NASDAQ: SCLXW)
SCLX vs SCLXW Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, SCLXW has a market cap of 33.6M. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while SCLXW trades at $0.10.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas SCLXW's P/E ratio is N/A. In terms of profitability, SCLX's ROE is +1.90%, compared to SCLXW's ROE of +1.90%. Regarding short-term risk, SCLX is less volatile compared to SCLXW. This indicates lower risk in terms of short-term price fluctuations for SCLX.Check SCLXW's competition here
BioDelivery Sciences Intl, Inc. Wrrt (NASDAQ: BDSIW)
SCLX vs BDSIW Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, BDSIW has a market cap of 0. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while BDSIW trades at $0.04.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas BDSIW's P/E ratio is -0.43. In terms of profitability, SCLX's ROE is +1.90%, compared to BDSIW's ROE of +0.57%. Regarding short-term risk, SCLX is less volatile compared to BDSIW. This indicates lower risk in terms of short-term price fluctuations for SCLX.Check BDSIW's competition here
Clarus Therapeutics Holdings, Inc. (NASDAQ: CRXT)
SCLX vs CRXT Comparison September 2026
Scilex Holding Company (NASDAQ: SCLX) plays a significant role within the Healthcare sector. Its performance on the NASDAQ reflects broader market trends and attracts considerable investor interest.
Comparing market capitalization, SCLX stands at 42.8M. In comparison, CRXT has a market cap of 0. Regarding current trading prices, SCLX is priced at $5.04 on the NASDAQ, while CRXT trades at $0.05.
To assess relative profitability and valuation, we examine the Return on Equity (ROE) and Price-to-Earnings (P/E) ratios.
SCLX currently has a P/E ratio of -0.13, whereas CRXT's P/E ratio is -0.02. In terms of profitability, SCLX's ROE is +1.90%, compared to CRXT's ROE of -4.63%. Regarding short-term risk, SCLX is less volatile compared to CRXT. This indicates lower risk in terms of short-term price fluctuations for SCLX.Check CRXT's competition here